研究人員確定了兒童敗血症風險的預測因素

昆士蘭大學的研究人員發現了兒童敗血症的預測因子。透過分析 900 多名重症兒童的血液樣本，他們可以在 24 小時內預測哪些兒童有敗血症和隨後器官衰竭的風險。這項發現意義重大，因為敗血症的早期發現對於挽救生命至關重要，使臨床醫生能夠及時採取乾預措施。

Can We Predict Sepsis in Kids?

我們可以預測兒童敗血症嗎？

Researchers at the University of Queensland have devised a way to predict whether a child is at risk of developing sepsis and subsequent organ failure.

昆士蘭大學的研究人員設計了一種方法來預測兒童是否有敗血症和隨後的器官衰竭的風險。

How Did They Do It?

他們是如何做到的呢？

"We analyzed blood samples from over 900 critically ill kids," explains Dr. Lachlan Coin, an associate professor at UQ's Institute for Molecular Bioscience. "By studying gene expression patterns, we could identify who would develop organ failure within 24 hours."

「我們分析了 900 多名危重兒童的血液樣本，」昆士蘭大學分子生物科學研究所副教授 Lachlan Coin 博士解釋道。 “透過研究基因表現模式，我們可以確定誰會在 24 小時內出現器官衰竭。”

What's the Significance?

有什麼意義？

"Sepsis is a life-threatening condition," says Professor Luregn Schlapbach from UQ's Child Health Research Centre. "Early detection is crucial, and this discovery could empower clinicians."

「敗血症是一種危及生命的疾病，」昆士蘭大學兒童健康研究中心的 Luregn Schlapbach 教授說。 “早期發現至關重要，這一發現可以為臨床醫生提供幫助。”

Why Is It So Tricky to Diagnose Sepsis?

為什麼診斷膿毒症如此困難？

"Many childhood illnesses mimic sepsis," Professor Schlapbach explains. "Without specific markers, it's hard to tell who's at risk."

「許多兒童疾病類似於敗血症，」施拉巴赫教授解釋。 “如果沒有特定的標記，很難判斷誰面臨風險。”

What's the Current Treatment Approach?

目前的治療方法是什麼？

"If sepsis is suspected, doctors give antibiotics, fluids, and increased observation," says Professor Schlapbach. "But this approach can lead to unnecessary treatment."

「如果懷疑敗血症，醫生會給予抗生素、液體並加強觀察，」施拉巴赫教授說。 “但這種方法可能會導致不必要的治療。”

What's Next?

下一步是什麼？

"We need more research before we can implement this discovery in clinical practice," Professor Schlapbach says. "Our goal is to develop a point-of-care platform that can generate results from a blood test within an hour."

「我們需要更多的研究才能將這項發現應用於臨床實踐，」施拉巴赫教授說。 “我們的目標是開發一個可以在一小時內產生血液檢測結果的即時護理平台。”

Who's Behind the Research?

誰是這項研究的幕後推手？

This study was funded by various organizations, including the Australian Government Medical Research Future Fund and the Children's Hospital Foundation Queensland. Dr. Coin also holds a professorship at the Doherty Institute at the University of Melbourne.

這項研究由多個組織資助，包括澳洲政府醫學研究未來基金和昆士蘭兒童醫院基金會。 Coin 博士也擔任墨爾本大學多爾蒂研究所的教授職位。

Where Can I Find the Study?

在哪裡可以找到該研究？

The research paper was published in the journal Lancet Child and Adolescent Health.

研究論文發表在《刺胳針兒童與青少年健康》期刊。

Media Contact

媒體聯繫

For media inquiries, contact the UQ Faculty of Medicine Communications team at med.media@uq.edu.au or +61 436 368 746.

如需媒體諮詢，請聯絡昆士蘭大學醫學院傳播團隊：med.media@uq.edu.au 或 +61 436 368 746。