Researchers Identify Predictor for Sepsis Risk in Children

Researchers at the University of Queensland have identified a predictor for sepsis in children. By analyzing blood samples from over 900 critically ill kids, they could predict which ones were at risk of developing sepsis and subsequent organ failure within 24 hours. This discovery is significant as early detection of sepsis is crucial in saving lives, empowering clinicians to take timely interventions.

Can We Predict Sepsis in Kids?

Researchers at the University of Queensland have devised a way to predict whether a child is at risk of developing sepsis and subsequent organ failure.

How Did They Do It?

"We analyzed blood samples from over 900 critically ill kids," explains Dr. Lachlan Coin, an associate professor at UQ's Institute for Molecular Bioscience. "By studying gene expression patterns, we could identify who would develop organ failure within 24 hours."

What's the Significance?

"Sepsis is a life-threatening condition," says Professor Luregn Schlapbach from UQ's Child Health Research Centre. "Early detection is crucial, and this discovery could empower clinicians."

Why Is It So Tricky to Diagnose Sepsis?

"Many childhood illnesses mimic sepsis," Professor Schlapbach explains. "Without specific markers, it's hard to tell who's at risk."

What's the Current Treatment Approach?

"If sepsis is suspected, doctors give antibiotics, fluids, and increased observation," says Professor Schlapbach. "But this approach can lead to unnecessary treatment."

What's Next?

"We need more research before we can implement this discovery in clinical practice," Professor Schlapbach says. "Our goal is to develop a point-of-care platform that can generate results from a blood test within an hour."

Who's Behind the Research?

This study was funded by various organizations, including the Australian Government Medical Research Future Fund and the Children's Hospital Foundation Queensland. Dr. Coin also holds a professorship at the Doherty Institute at the University of Melbourne.

Where Can I Find the Study?

The research paper was published in the journal Lancet Child and Adolescent Health.

Media Contact

For media inquiries, contact the UQ Faculty of Medicine Communications team at med.media@uq.edu.au or +61 436 368 746.