fic 顧問委員會由世界著名的長壽科學家組成，其中包括 David Sinclair 博士輸出：標題：去中心化科學（DeSci）：透過透明度、開放性和公平性重新定義科學研究

DeSci作為Web3技術在科學研究領域的創新應用，正在解決傳統科學（TradSci）的核心痛點

scientific committee consists of experts in longevity science, biomedicine, and Web3 technology, who provide professional guidance and support for scientific research project selection and evaluation.

科學委員會由長壽科學、生物醫學、Web3技術領域的專家組成，為科學研究計畫的選擇和評估提供專業指導和支援。

As a decentralized scientific research organization, VitaDAO combines the strengths of Web3 technology and the longevity science community to efficiently allocate funds and support promising research projects. Through the VitaDAO platform, a total of 11 scientific research projects have been funded so far, covering research directions such as aging biology, longevity biomarkers, and senolytic drug development. Among them, the research project on aging biology and longevity biomarkers has received strong support from the community and obtained a total funding of more than 2.2 million US dollars. In addition, VitaDAO also provides intellectual property management services for funded projects, aiming to maximize the commercial value of scientific research results and promote the development of longevity science.

作為一個去中心化的科學研究組織，VitaDAO 結合了 Web3 技術和長壽科學社群的優勢，高效分配資金並支持有前途的研究計畫。透過VitaDAO平台，迄今共資助了11個科學研究項目，涵蓋老化生物學、長壽生物標記、抗老藥物開發等研究方向。其中，老化生物學和長壽生物標記研究計畫得到了社會各界的大力支持，獲得總經費超過220萬美元。此外，VitaDAO也為資助計畫提供智慧財產權管理服務，旨在最大化科學研究成果的商業價值，推動長壽科學的發展。

Sci-Hub

科學中心

Sci-Hub is a non-profit shadow library that provides free and illegal access to millions of research papers and academic articles, bypassing publisher paywalls. Founded in 2011 by Alexandra Elbakyan, a Kazakhstani neuroscientist, Sci-Hub has faced numerous legal challenges and controversies over the years. However, it remains a popular resource for researchers, students, and the general public in countries with limited access to scientific literature.

Sci-Hub 是一個非營利影子圖書館，繞過出版商的付費牆，提供對數百萬篇研究論文和學術文章的免費和非法訪問。 Sci-Hub 由哈薩克神經科學家 Alexandra Elbakyan 於 2011 年創立，多年來面臨無數法律挑戰和爭議。然而，對於科學文獻獲取有限的國家的研究人員、學生和公眾來說，它仍然是一種受歡迎的資源。

Sci-Hub's operating principle is simple: users enter the DOI or PMID of the desired article into the Sci-Hub website or Telegram bot. If the article is available, Sci-Hub will automatically download and deliver it to the user. This process usually takes a few seconds to complete. Sci-Hub obtains articles from various sources, including university libraries, institutional repositories, and individual researchers who share their copies of articles.

Sci-Hub 的操作原理很簡單：使用者將所需文章的 DOI 或 PMID 輸入到 Sci-Hub 網站或 Telegram 機器人。如果文章可用，Sci-Hub 將自動下載並將其傳送給使用者。此過程通常需要幾秒鐘才能完成。 Sci-Hub 從各種來源獲取文章，包括大學圖書館、機構知識庫以及共享文章副本的個人研究人員。

Sci-Hub's activities have sparked heated debate within the academic and publishing communities. Supporters argue that Sci-Hub promotes the free flow of scientific knowledge and makes research accessible to all, regardless of their ability to pay or geographical location. They also point out that Sci-Hub does not host any copyrighted materials and that its activities fall under the fair use doctrine.

Sci-Hub 的活動引發了學術界和出版界的激烈爭論。支持者認為，Sci-Hub 促進了科學知識的自由流動，並使所有人都能獲得研究成果，無論其支付能力或地理位置如何。他們還指出，Sci-Hub 不託管任何受版權保護的資料，其活動符合合理使用原則。

Critics, on the other hand, maintain that Sci-Hub engages in large-scale copyright infringement and undermines the financial viability of scientific publishers. They argue that publishers play a crucial role in the dissemination, peer review, and preservation of scientific knowledge and that Sci-Hub's actions threaten the sustainability of these services.

另一方面，批評者認為 Sci-Hub 存在大規模版權侵權行為，並損害了科學出版商的財務生存能力。他們認為，出版商在科學知識的傳播、同行評審和保存方面發揮著至關重要的作用，而 Sci-Hub 的行為威脅到了這些服務的可持續性。

Despite the legal challenges and controversies, Sci-Hub continues to operate and remains a valuable resource for many researchers and students around the world. Its impact on the accessibility and dissemination of scientific knowledge is undeniable, and it is likely to remain a topic of discussion and debate for years to come.output: DeSci, short for decentralized science, is a new scientific research model that integrates blockchain technology with scientific research. It aims to solve the problems of traditional scientific research, such as concentrated resources, opaque management, and limited knowledge dissemination, and build a more transparent, fair, and open scientific research ecosystem.

儘管面臨法律挑戰和爭議，Sci-Hub 仍在繼續運營，並且仍然是世界各地許多研究人員和學生的寶貴資源。它對科學知識的獲取和傳播的影響是不可否認的，並且很可能在未來幾年仍然是討論和爭論的話題。科學研究。旨在解決傳統科學研究資源集中、管理不透明、知識傳播有限等問題，建構更透明、公平、開放的科學研究生態系統。

As an emerging field, DeSci has attracted attention from various parties due to its innovative concepts and potential to disrupt traditional scientific research. However, due to the early stage of development and the particularity of scientific research, DeSci also faces challenges in terms of market liquidity, scientific research feedback loops, and mainstream narrative.

作為一個新興領域，DeSci 因其創新理念和顛覆傳統科學研究的潛力而受到各方關注。但由於發展初期以及科學研究的特殊性，DeSci 也面臨市場流動性、科學研究回饋循環、主流敘事等方面的挑戰。

DeSci's strengths lie in its ability to break down barriers in scientific research funding, improve research accessibility and transparency, encourage wider community participation and collaboration, and provide new governance and funding models for scientific research. Just as the open source software revolution has changed the landscape of technology development, DeSci is also expected to become the "open source movement" in the field of scientific research, carrying the vision of fair distribution of resources and becoming an accelerator of scientific democratization, returning the future of scientific research to the global community.

DeSci 的優勢在於能夠打破科學研究資助障礙，提高研究的可近性和透明度，鼓勵更廣泛的社區參與和協作，並為科學研究提供新的治理和資助模式。正如開源軟體革命改變了技術發展的面貌一樣，DeSci也有望成為科研領域的“開源運動”，承載著資源公平分配的願景，成為科學民主化的加速器，將科學研究的未來還給國際社會。

DeSci's methods and use cases mainly include:

DeSci的方法和用例主要包括：

1. Fairness and decentralization of fund allocation: DeSci uses a secondary donation mechanism and decentralized autonomous organizations (DAOs) to achieve transparent management and distribution of funds through smart contracts. This mechanism not only lowers the threshold for researchers to obtain funds but also provides support for innovative and diverse scientific research projects and promotes the fair allocation of global scientific research resources.

1. 資金分配的公平性和去中心化：DeSci 採用二級捐贈機制和去中心化自治組織（DAO），透過智慧合約實現資金的透明管理和分配。這項機制不僅降低了科學研究人員取得經費的門檻，也為創新、多樣化的科學研究計畫提供了支持，促進了全球研究資源的公平配置。

2. Openness and security of data and publications: DeSci stores scientific research data and publications on a public ledger through a decentralized research repository based on blockchain, ensuring that the results are traceable and transparent. Smart contracts provide a fair distribution mechanism for data access, enabling researchers and institutions to share and use key data resources while protecting intellectual property rights.

2.資料和出版物的開放性和安全性：DeSci透過基於區塊鏈的去中心化研究儲存庫將科學研究資料和出版物儲存在公共帳本上，確保結果可追溯和透明。智慧合約為資料存取提供了公平的分配機制，使研究人員和機構能夠共享和使用關鍵資料資源，同時保護智慧財產權。

3. Promoting the reproducibility of scientific research, in which validation experiments and data reproducibility are crucial. DeSci rewards reproducible research practices by introducing token incentive mechanisms and reputation systems. Blockchain-based smart contracts also support a transparent peer review process to ensure the reliability and authenticity of scientific research findings.

3. 提高科學研究的可重複性，其中驗證實驗和數據可重複性至關重要。 DeSci 透過引入代幣激勵機制和聲譽系統來獎勵可重複的研究實踐。基於區塊鏈的智慧合約也支援透明的同儕審查流程，以確保科學研究結果的可靠性和真實性。

DeSci's four major use cases in practice include decentralization of academic publishing, transparent management of research funding, innovative models for data sharing and collaboration

DeSci 在實踐中的四大用例包括學術出版的去中心化、研究經費的透明管理、數據共享和協作的創新模式