fic 顾问委员会由世界著名的长寿科学家组成，其中包括 David Sinclair 博士输出：标题：去中心化科学（DeSci）：通过透明度、开放性和公平性重新定义科学研究

DeSci作为Web3技术在科学研究领域的创新应用，正在解决传统科学（TradSci）的核心痛点

scientific committee consists of experts in longevity science, biomedicine, and Web3 technology, who provide professional guidance and support for scientific research project selection and evaluation.

科学委员会由长寿科学、生物医学、Web3技术领域的专家组成，为科研项目的选择和评估提供专业指导和支持。

As a decentralized scientific research organization, VitaDAO combines the strengths of Web3 technology and the longevity science community to efficiently allocate funds and support promising research projects. Through the VitaDAO platform, a total of 11 scientific research projects have been funded so far, covering research directions such as aging biology, longevity biomarkers, and senolytic drug development. Among them, the research project on aging biology and longevity biomarkers has received strong support from the community and obtained a total funding of more than 2.2 million US dollars. In addition, VitaDAO also provides intellectual property management services for funded projects, aiming to maximize the commercial value of scientific research results and promote the development of longevity science.

作为一个去中心化的科学研究组织，VitaDAO 结合了 Web3 技术和长寿科学社区的优势，高效分配资金并支持有前途的研究项目。通过VitaDAO平台，迄今为止共资助了11个科研项目，涵盖衰老生物学、长寿生物标志物、抗衰老药物开发等研究方向。其中，衰老生物学和长寿生物标志物研究项目得到了社会各界的大力支持，获得总经费超过220万美元。此外，VitaDAO还为资助项目提供知识产权管理服务，旨在最大化科研成果的商业价值，推动长寿科学的发展。

Sci-Hub

科学中心

Sci-Hub is a non-profit shadow library that provides free and illegal access to millions of research papers and academic articles, bypassing publisher paywalls. Founded in 2011 by Alexandra Elbakyan, a Kazakhstani neuroscientist, Sci-Hub has faced numerous legal challenges and controversies over the years. However, it remains a popular resource for researchers, students, and the general public in countries with limited access to scientific literature.

Sci-Hub 是一个非营利性影子图书馆，绕过出版商的付费墙，提供对数百万篇研究论文和学术文章的免费和非法访问。 Sci-Hub 由哈萨克斯坦神经科学家 Alexandra Elbakyan 于 2011 年创立，多年来面临着无数法律挑战和争议。然而，对于科学文献获取有限的国家的研究人员、学生和公众来说，它仍然是一种受欢迎的资源。

Sci-Hub's operating principle is simple: users enter the DOI or PMID of the desired article into the Sci-Hub website or Telegram bot. If the article is available, Sci-Hub will automatically download and deliver it to the user. This process usually takes a few seconds to complete. Sci-Hub obtains articles from various sources, including university libraries, institutional repositories, and individual researchers who share their copies of articles.

Sci-Hub 的操作原理很简单：用户将所需文章的 DOI 或 PMID 输入到 Sci-Hub 网站或 Telegram 机器人中。如果该文章可用，Sci-Hub 将自动下载并将其传送给用户。此过程通常需要几秒钟才能完成。 Sci-Hub 从各种来源获取文章，包括大学图书馆、机构知识库以及共享文章副本的个人研究人员。

Sci-Hub's activities have sparked heated debate within the academic and publishing communities. Supporters argue that Sci-Hub promotes the free flow of scientific knowledge and makes research accessible to all, regardless of their ability to pay or geographical location. They also point out that Sci-Hub does not host any copyrighted materials and that its activities fall under the fair use doctrine.

Sci-Hub 的活动引发了学术界和出版界的激烈争论。支持者认为，Sci-Hub 促进了科学知识的自由流动，并使所有人都能获得研究成果，无论其支付能力或地理位置如何。他们还指出，Sci-Hub 不托管任何受版权保护的材料，其活动符合合理使用原则。

Critics, on the other hand, maintain that Sci-Hub engages in large-scale copyright infringement and undermines the financial viability of scientific publishers. They argue that publishers play a crucial role in the dissemination, peer review, and preservation of scientific knowledge and that Sci-Hub's actions threaten the sustainability of these services.

另一方面，批评者认为 Sci-Hub 存在大规模版权侵权行为，并损害了科学出版商的财务生存能力。他们认为，出版商在科学知识的传播、同行评审和保存方面发挥着至关重要的作用，而 Sci-Hub 的行为威胁到了这些服务的可持续性。

Despite the legal challenges and controversies, Sci-Hub continues to operate and remains a valuable resource for many researchers and students around the world. Its impact on the accessibility and dissemination of scientific knowledge is undeniable, and it is likely to remain a topic of discussion and debate for years to come.output: DeSci, short for decentralized science, is a new scientific research model that integrates blockchain technology with scientific research. It aims to solve the problems of traditional scientific research, such as concentrated resources, opaque management, and limited knowledge dissemination, and build a more transparent, fair, and open scientific research ecosystem.

尽管面临法律挑战和争议，Sci-Hub 仍在继续运营，并且仍然是世界各地许多研究人员和学生的宝贵资源。它对科学知识的获取和传播的影响是不可否认的，并且很可能在未来几年仍然是讨论和争论的话题。 输出：DeSci，去中心化科学的缩写，是一种将区块链技术与科学研究。旨在解决传统科学研究资源集中、管理不透明、知识传播有限等问题，构建更加透明、公平、开放的科研生态系统。

As an emerging field, DeSci has attracted attention from various parties due to its innovative concepts and potential to disrupt traditional scientific research. However, due to the early stage of development and the particularity of scientific research, DeSci also faces challenges in terms of market liquidity, scientific research feedback loops, and mainstream narrative.

作为一个新兴领域，DeSci 因其创新理念和颠覆传统科学研究的潜力而受到各方关注。但由于发展初期以及科研的特殊性，DeSci 也面临着市场流动性、科研反馈循环、主流叙事等方面的挑战。

DeSci's strengths lie in its ability to break down barriers in scientific research funding, improve research accessibility and transparency, encourage wider community participation and collaboration, and provide new governance and funding models for scientific research. Just as the open source software revolution has changed the landscape of technology development, DeSci is also expected to become the "open source movement" in the field of scientific research, carrying the vision of fair distribution of resources and becoming an accelerator of scientific democratization, returning the future of scientific research to the global community.

DeSci 的优势在于能够打破科研资助障碍，提高研究的可及性和透明度，鼓励更广泛的社区参与和协作，并为科学研究提供新的治理和资助模式。正如开源软件革命改变了技术发展的面貌一样，DeSci也有望成为科研领域的“开源运动”，承载着资源公平分配的愿景，成为科学民主化的加速器，将科学研究的未来还给国际社会。

DeSci's methods and use cases mainly include:

DeSci的方法和用例主要包括：

1. Fairness and decentralization of fund allocation: DeSci uses a secondary donation mechanism and decentralized autonomous organizations (DAOs) to achieve transparent management and distribution of funds through smart contracts. This mechanism not only lowers the threshold for researchers to obtain funds but also provides support for innovative and diverse scientific research projects and promotes the fair allocation of global scientific research resources.

1. 资金分配的公平性和去中心化：DeSci 采用二级捐赠机制和去中心化自治组织（DAO），通过智能合约实现资金的透明管理和分配。这一机制不仅降低了科研人员获得经费的门槛，也为创新型、多样化的科研项目提供了支持，促进了全球科研资源的公平配置。

2. Openness and security of data and publications: DeSci stores scientific research data and publications on a public ledger through a decentralized research repository based on blockchain, ensuring that the results are traceable and transparent. Smart contracts provide a fair distribution mechanism for data access, enabling researchers and institutions to share and use key data resources while protecting intellectual property rights.

2.数据和出版物的开放性和安全性：DeSci通过基于区块链的去中心化研究存储库将科研数据和出版物存储在公共账本上，确保结果可追溯和透明。智能合约为数据访问提供了公平的分配机制，使研究人员和机构能够共享和使用关键数据资源，同时保护知识产权。

3. Promoting the reproducibility of scientific research, in which validation experiments and data reproducibility are crucial. DeSci rewards reproducible research practices by introducing token incentive mechanisms and reputation systems. Blockchain-based smart contracts also support a transparent peer review process to ensure the reliability and authenticity of scientific research findings.

3. 促进科学研究的可重复性，其中验证实验和数据可重复性至关重要。 DeSci 通过引入代币激励机制和声誉系统来奖励可重复的研究实践。基于区块链的智能合约还支持透明的同行评审流程，以确保科学研究结果的可靠性和真实性。

DeSci's four major use cases in practice include decentralization of academic publishing, transparent management of research funding, innovative models for data sharing and collaboration

DeSci 在实践中的四大用例包括学术出版的去中心化、研究经费的透明管理、数据共享和协作的创新模式