An Overview of Popular Memes Driven by AI Agents and DeSci

re, YBB Capital Researcher

In the past six months, a new emerging force surrounding AI Agents and DeSci has swept the market. From the perspective of meme-driven narratives, AI Agents focus on their strong potential in autonomous decision-making, data analysis, and task execution, excelling at solving problems through algorithms; meanwhile, DeSci aims to leverage blockchain technology to break traditional research barriers, achieve data sharing and transparency, and promote decentralized knowledge sharing and research funding. This article will summarize and categorize the currently relatively hot and potentially influential meme-related tokens in the market based on the two major directions of AI Agents and DeSci.

1. AI Agent: Intelligent AI 'Carriage'

1.1 What is an AI Agent?

AI Agent refers to intelligent systems with autonomy and goal-oriented features, capable of sensing the environment, planning actions, executing tasks, and learning from experience without human intervention to achieve specific goals. For example, an AI Agent can autonomously monitor data, analyze anomalies, and make decisions. The key lies in 'autonomy' and 'goal-driven'.

According to Messari data as of December s31, 2024, the current AI craze resembles the situation before the early DeFi explosion of 2020–2021. The next day, A16z proposed some ideas for AI Agents in 2025: AI Agents need independent wallets, decentralized chatbots; and with the widespread use of artificial intelligence, there is a need for 'personal proofs' for different AI entities.

1.2 Overview of Popular Tokens

> Note: The following rankings are based on dynamic Mindshare consumer mental share rates provided by Cookie DAO.

1. AIXBT (@aixbt_agent)

- Market Cap: $550 million, Mind Share: 20.7%

- Introduction: 'AIXBT tracks popular discussions on crypto Twitter, using a self-developed engine to identify strong narratives and trends... AIXBT token holders can use its analysis platform.'

2. Virtuals (@virtuals_io)

- Market Cap: $4 billion, Mind Share: 20.7%

- Introduction: Virtuals designed an IAO (Initial Asset Offering) model that allows users to lock $VIRTUAL to generate new AI Agents, with the generated tokens automatically forming liquidity pools paired with locked $VIRTUAL. According to Dune data from January 1, nearly 13,000 AI Agents have been generated through Virtuals.

Source Data: Dune:@hashed_official/Virtuals Protocol’s AI Agent Launchpad

3. AI16Z (@ai16zdao)

- Market Cap: $2 billion, Mind Share: 8.57%

- Introduction: The structure of this project and the relationships between various entities are relatively complex: ai16z is a decentralized DAO that includes both ai16z and degenai tokens; ElizaOS is an open-source AI Agent framework; Eliza Labs is responsible for the development of ElizaOS; the ELIZA token is developed and supported by an independent team but is not an official product.

4. Fartcoin (@FartCoinOfSOL)

- Market Cap: $900 million, Mind Share: 6.93%

- Introduction: Fartcoin belongs to the Solana ecosystem, conceived by Terminal of Truth (CTO), allowing users to submit jokes or memes related to farting in exchange for tokens; simultaneously, a self-aware robot is responsible for tokenizing 'fart'.

5. Zerebro (@0xzerebro)

- Market Cap: $560 million, Mind Share: 4.36%

- Introduction: Zerebro focuses on autonomous AI Agents for art creation and content generation, capable of independently creating music, memes, artworks, and NFTs while interacting and operating on platforms such as Twitter, Instagram, Spotify, Polygon, etc.

6. Griffain (@griffaindotcom)

- Market Cap: $380 million, Mind Share: 3.53%

- Introduction: Griffain is a new AI Agent built on the Solana blockchain, aimed at providing users with a simpler way to interact with cryptocurrencies by merging personal and professional AI Agents. It can automatically perform wallet management, token trading, NFT minting, and other tasks.

7. SNAI (@swarmnode)

- Market Cap: $83 million, Mind Share: 1.95%

- Introduction: SNAI is the token corresponding to the cloud server protocol SwarmNode.ai (SNAI) Agent platform.

8. GOAT (@truth_terminal)

- Market Cap: $560 million, Mind Share: 1.91%

- Introduction: Gospel of Goatse is a meme coin initiated by the Pump Fun platform, fine-tuned by the AI platform Terminal of Truth, and trained on data sources like Reddit and 4chan.